Season the Chicken: In a large mixing bowl, combine the ground chicken, garlic powder, onion powder, paprika, salt, and pepper. Mix thoroughly until the spices are evenly integrated.
Form the Patties: Divide the seasoned chicken into 4 equal portions and shape them into round, flat patties.
Set Up the Breading Station: Prepare three shallow bowls:
Bowl 1: All-purpose flour.
Bowl 2: The egg and milk (whisked together).
Bowl 3: Panko breadcrumbs.
Dredge & Coat: Coat each chicken patty in the flour (shake off excess), dip into the egg mixture, and then press firmly into the panko breadcrumbs for an even crust.
Prep the Air Fryer: Preheat your air fryer to 375°F (190°C). Lightly mist both sides of the breaded patties with cooking spray or light oil.
Air Fry: Place the patties in the basket and cook for 8–10 minutes per side. The patties are done when the exterior is golden brown and the internal temperature reaches 165°F (74°C).
Whisk the Sauce: While the chicken cooks, combine the mayonnaise and lemon juice in a small bowl to create the tangy sandwich spread.
Toast the Buns: Lightly toast your burger buns until golden and warm.
Assemble: Spread a generous layer of the lemon-mayo sauce on both the top and bottom buns. Place a crispy patty on the base, pile on the shredded lettuce, and add the top bun.
Serve: Enjoy immediately while the chicken is hot and the lettuce is crisp!